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p38α MAPK-mediated induction and interaction of FOXO3a and p53 contribute to the inhibited-growth and induced-apoptosis of human lung adenocarcinoma cells by berberine
BACKGROUND: Berberine (BBR), a component from traditional Chinese medicine, has been shown to possess anti-tumor activity against a wide spectrum of cancer cells including human lung cancer, but the detailed mechanism underlining this has not been well elucidated. METHODS: In this study, the effect...
Autores principales: | Zheng, Fang, Tang, Qin, Wu, JingJing, Zhao, ShunYu, Liang, ZhanYang, Li, Liuning, Wu, WanYin, Hann, Swei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013801/ https://www.ncbi.nlm.nih.gov/pubmed/24766860 http://dx.doi.org/10.1186/1756-9966-33-36 |
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