Valproic acid triggers increased mitochondrial biogenesis in POLG-deficient fibroblasts

Valproic acid (VPA) is a widely used antiepileptic drug and also prescribed to treat migraine, chronic headache and bipolar disorder. Although it is usually well tolerated, a severe hepatotoxic reaction has been repeatedly reported after VPA administration. A profound toxic reaction on administratio...

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Detalles Bibliográficos
Autores principales: Sitarz, Kamil S., Elliott, Hannah R., Karaman, Betül S., Relton, Caroline, Chinnery, Patrick F., Horvath, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013927/
https://www.ncbi.nlm.nih.gov/pubmed/24725338
http://dx.doi.org/10.1016/j.ymgme.2014.03.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013927/
https://www.ncbi.nlm.nih.gov/pubmed/24725338
http://dx.doi.org/10.1016/j.ymgme.2014.03.006

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