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Valproic acid triggers increased mitochondrial biogenesis in POLG-deficient fibroblasts
Valproic acid (VPA) is a widely used antiepileptic drug and also prescribed to treat migraine, chronic headache and bipolar disorder. Although it is usually well tolerated, a severe hepatotoxic reaction has been repeatedly reported after VPA administration. A profound toxic reaction on administratio...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013927/ https://www.ncbi.nlm.nih.gov/pubmed/24725338 http://dx.doi.org/10.1016/j.ymgme.2014.03.006 |