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A Rapid Assay for Measuring Nucleotide Excision Repair by Oligonucleotide Retrieval

Nucleotide excision repair (NER) excises bulky DNA lesions induced by mutagens and carcinogens. The repair process includes recognition of DNA damage, excision of a short patch of nucleotides containing the damaged base, re-synthesis of a new DNA strand and ligation of the nicks to restore the seque...

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Detalles Bibliográficos
Autores principales: Shen, Jiang-Cheng, Fox, Edward J., Ahn, Eun Hyun, Loeb, Lawrence A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013936/
https://www.ncbi.nlm.nih.gov/pubmed/24809800
http://dx.doi.org/10.1038/srep04894