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A PrP(C)-caveolin-Lyn complex negatively controls neuronal GSK3β and serotonin 1B receptor

The cellular prion protein, PrP(C), is a glycosylphosphatidylinositol-anchored protein, abundant in lipid rafts and highly expressed in the brain. While PrP(C) is much studied for its involvement under its abnormal PrP(Sc) isoform in Transmissible Spongiform Encephalopathies, its physiological role...

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Detalles Bibliográficos
Autores principales: Hernandez-Rapp, Julia, Martin-Lannerée, Séverine, Hirsch, Théo Z., Pradines, Elodie, Alleaume-Butaux, Aurélie, Schneider, Benoît, Baudry, Anne, Launay, Jean-Marie, Mouillet-Richard, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013941/
https://www.ncbi.nlm.nih.gov/pubmed/24810941
http://dx.doi.org/10.1038/srep04881