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A PrP(C)-caveolin-Lyn complex negatively controls neuronal GSK3β and serotonin 1B receptor
The cellular prion protein, PrP(C), is a glycosylphosphatidylinositol-anchored protein, abundant in lipid rafts and highly expressed in the brain. While PrP(C) is much studied for its involvement under its abnormal PrP(Sc) isoform in Transmissible Spongiform Encephalopathies, its physiological role...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013941/ https://www.ncbi.nlm.nih.gov/pubmed/24810941 http://dx.doi.org/10.1038/srep04881 |