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Increased radiosensitivity and radiation-induced apoptosis in SRC-3 knockout mice

Steroid receptor coactivator-3 (SRC-3), a multifunctional transcriptional coactivator, plays an important role in regulation of cell apoptosis in chemoresistant cancer cells. However, its role in radiation-induced apoptosis in hematopoietic cells is still unclear. In this study, we used SRC-3 knocko...

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Detalles Bibliográficos
Autores principales: Jin, Jie, Wang, Yu, Wang, Jin, Xu, Yang, Chen, Shilei, Wang, Junping, Ran, Xinze, Su, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014155/
https://www.ncbi.nlm.nih.gov/pubmed/24309719
http://dx.doi.org/10.1093/jrr/rrt132