An Unbiased Proteomic Screen Reveals Caspase Cleavage Is Positively and Negatively Regulated by Substrate Phosphorylation

Post-translational modifications of proteins regulate diverse cellular functions, with mounting evidence suggesting that hierarchical cross-talk between distinct modifications may fine-tune cellular responses. For example, in apoptosis, caspases promote cell death via cleavage of key structural and...

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Detalles Bibliográficos
Autores principales: Turowec, Jacob P., Zukowski, Stephanie A., Knight, James D. R., Smalley, David M., Graves, Lee M., Johnson, Gary L., Li, Shawn S. C., Lajoie, Gilles A., Litchfield, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014278/
https://www.ncbi.nlm.nih.gov/pubmed/24556848
http://dx.doi.org/10.1074/mcp.M113.037374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014278/
https://www.ncbi.nlm.nih.gov/pubmed/24556848
http://dx.doi.org/10.1074/mcp.M113.037374

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