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Synonymous Constraint Elements Show a Tendency to Encode Intrinsically Disordered Protein Segments

Synonymous constraint elements (SCEs) are protein-coding genomic regions with very low synonymous mutation rates believed to carry additional, overlapping functions. Thousands of such potentially multi-functional elements were recently discovered by analyzing the levels and patterns of evolutionary...

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Detalles Bibliográficos
Autores principales: Macossay-Castillo, Mauricio, Kosol, Simone, Tompa, Peter, Pancsa, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014394/
https://www.ncbi.nlm.nih.gov/pubmed/24809503
http://dx.doi.org/10.1371/journal.pcbi.1003607