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Synonymous Constraint Elements Show a Tendency to Encode Intrinsically Disordered Protein Segments
Synonymous constraint elements (SCEs) are protein-coding genomic regions with very low synonymous mutation rates believed to carry additional, overlapping functions. Thousands of such potentially multi-functional elements were recently discovered by analyzing the levels and patterns of evolutionary...
Autores principales: | Macossay-Castillo, Mauricio, Kosol, Simone, Tompa, Peter, Pancsa, Rita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014394/ https://www.ncbi.nlm.nih.gov/pubmed/24809503 http://dx.doi.org/10.1371/journal.pcbi.1003607 |
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