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A Computational Framework for Analyzing Stochasticity in Gene Expression

Stochastic fluctuations in gene expression give rise to distributions of protein levels across cell populations. Despite a mounting number of theoretical models explaining stochasticity in protein expression, we lack a robust, efficient, assumption-free approach for inferring the molecular mechanism...

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Detalles Bibliográficos
Autores principales: Sherman, Marc S., Cohen, Barak A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014403/
https://www.ncbi.nlm.nih.gov/pubmed/24811315
http://dx.doi.org/10.1371/journal.pcbi.1003596