Knocking down CDK4 mediates the elevation of let-7c suppressing cell growth in nasopharyngeal carcinoma

BACKGROUND: CDK4 is a protein kinase in the CDK family important for G1/S phase cell cycle progression. However, the roles and molecular mechanisms of CDK4 triggering nasopharynx carcinogenesis are still unclear. METHODS: Lentiviral-vector mediated shRNA was used to suppress CDK4 expression and exam...

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Detalles Bibliográficos
Autores principales: Liu, Zhen, Long, Xiaobin, Chao, Cheng, Yan, Chen, Wu, Qiangyun, Hua, Shengni, Zhang, Yajie, Wu, Aibing, Fang, Weiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014407/
https://www.ncbi.nlm.nih.gov/pubmed/24751144
http://dx.doi.org/10.1186/1471-2407-14-274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014407/
https://www.ncbi.nlm.nih.gov/pubmed/24751144
http://dx.doi.org/10.1186/1471-2407-14-274

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