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Knocking down CDK4 mediates the elevation of let-7c suppressing cell growth in nasopharyngeal carcinoma
BACKGROUND: CDK4 is a protein kinase in the CDK family important for G1/S phase cell cycle progression. However, the roles and molecular mechanisms of CDK4 triggering nasopharynx carcinogenesis are still unclear. METHODS: Lentiviral-vector mediated shRNA was used to suppress CDK4 expression and exam...
Autores principales: | Liu, Zhen, Long, Xiaobin, Chao, Cheng, Yan, Chen, Wu, Qiangyun, Hua, Shengni, Zhang, Yajie, Wu, Aibing, Fang, Weiyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014407/ https://www.ncbi.nlm.nih.gov/pubmed/24751144 http://dx.doi.org/10.1186/1471-2407-14-274 |
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