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Cytokine Responses to the Anti-schistosome Vaccine Candidate Antigen Glutathione-S-transferase Vary with Host Age and Are Boosted by Praziquantel Treatment

BACKGROUND: Improved helminth control is required to alleviate the global burden of schistosomiasis and schistosome-associated pathologies. Current control efforts rely on the anti-helminthic drug praziquantel (PZQ), which enhances immune responses to crude schistosome antigens but does not prevent...

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Detalles Bibliográficos
Autores principales: Bourke, Claire D., Nausch, Norman, Rujeni, Nadine, Appleby, Laura J., Trottein, François, Midzi, Nicholas, Mduluza, Takafira, Mutapi, Francisca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014416/
https://www.ncbi.nlm.nih.gov/pubmed/24810615
http://dx.doi.org/10.1371/journal.pntd.0002846