Mlh2 Is an Accessory Factor for DNA Mismatch Repair in Saccharomyces cerevisiae

In Saccharomyces cerevisiae, the essential mismatch repair (MMR) endonuclease Mlh1-Pms1 forms foci promoted by Msh2-Msh6 or Msh2-Msh3 in response to mispaired bases. Here we analyzed the Mlh1-Mlh2 complex, whose role in MMR has been unclear. Mlh1-Mlh2 formed foci that often colocalized with and had...

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Detalles Bibliográficos
Autores principales: Campbell, Christopher S., Hombauer, Hans, Srivatsan, Anjana, Bowen, Nikki, Gries, Kerstin, Desai, Arshad, Putnam, Christopher D., Kolodner, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014439/
https://www.ncbi.nlm.nih.gov/pubmed/24811092
http://dx.doi.org/10.1371/journal.pgen.1004327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014439/
https://www.ncbi.nlm.nih.gov/pubmed/24811092
http://dx.doi.org/10.1371/journal.pgen.1004327

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