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L1 retrotransposition: The snap-velcro model and its consequences

LINE-1 (L1) elements are the only active and autonomous transposable elements in humans. The core retrotransposition machinery is a ribonucleoprotein particle (RNP) containing the L1 mRNA, with endonuclease and reverse transcriptase activities. It initiates reverse transcription directly at genomic...

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Detalles Bibliográficos
Autores principales: Viollet, Sébastien, Monot, Clément, Cristofari, Gaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014453/
https://www.ncbi.nlm.nih.gov/pubmed/24818067
http://dx.doi.org/10.4161/mge.28907