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Timed Action of IL-27 Protects from Immunopathology while Preserving Defense in Influenza

Infection with influenza virus can result in massive pulmonary infiltration and potentially fatal immunopathology. Understanding the endogenous mechanisms that control immunopathology could provide a key to novel adjunct therapies for this disease. Here we show that the cytokine IL-27 plays a crucia...

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Detalles Bibliográficos
Autores principales: Liu, Francesca Diane M., Kenngott, Elisabeth E., Schröter, Micha F., Kühl, Anja, Jennrich, Silke, Watzlawick, Ralf, Hoffmann, Ute, Wolff, Thorsten, Norley, Stephen, Scheffold, Alexander, Stumhofer, Jason S., Saris, Christiaan J. M., Schwab, Jan M., Hunter, Christopher A., Debes, Gudrun F., Hamann, Alf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014457/
https://www.ncbi.nlm.nih.gov/pubmed/24809349
http://dx.doi.org/10.1371/journal.ppat.1004110