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Identification of HIV-1 Vif Regions Required for CBF-β Interaction and APOBEC3 Suppression
Human immunodeficiency virus type 1 (HIV-1) Vif requires core binding factor β (CBF-β) to degrade the host APOBEC3 restriction factors. Although a minimum domain and certain amino acids of HIV-1 Vif, including hydrophobic residues at the N-terminal, have been identified as critical sites for binding...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014475/ https://www.ncbi.nlm.nih.gov/pubmed/24810617 http://dx.doi.org/10.1371/journal.pone.0095738 |