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Partial Agonist, Telmisartan, Maintains PPARγ Serine 112 Phosphorylation, and Does Not Affect Osteoblast Differentiation and Bone Mass

Peroxisome proliferator activated receptor gamma (PPARγ) controls both glucose metabolism and an allocation of marrow mesenchymal stem cells (MSCs) toward osteoblast and adipocyte lineages. Its activity is determined by interaction with a ligand which directs posttranscriptional modifications of PPA...

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Detalles Bibliográficos
Autores principales: Kolli, Vipula, Stechschulte, Lance A., Dowling, Abigail R., Rahman, Sima, Czernik, Piotr J., Lecka-Czernik, Beata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014504/
https://www.ncbi.nlm.nih.gov/pubmed/24810249
http://dx.doi.org/10.1371/journal.pone.0096323