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Partial Agonist, Telmisartan, Maintains PPARγ Serine 112 Phosphorylation, and Does Not Affect Osteoblast Differentiation and Bone Mass
Peroxisome proliferator activated receptor gamma (PPARγ) controls both glucose metabolism and an allocation of marrow mesenchymal stem cells (MSCs) toward osteoblast and adipocyte lineages. Its activity is determined by interaction with a ligand which directs posttranscriptional modifications of PPA...
Autores principales: | Kolli, Vipula, Stechschulte, Lance A., Dowling, Abigail R., Rahman, Sima, Czernik, Piotr J., Lecka-Czernik, Beata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014504/ https://www.ncbi.nlm.nih.gov/pubmed/24810249 http://dx.doi.org/10.1371/journal.pone.0096323 |
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