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A Novel TetR-Regulating Peptide Turns off rtTA-Mediated Activation of Gene Expression

Conditional regulation of gene expression is a powerful and indispensable method for analyzing gene function. The “Tet-On” system is a tool widely used for that purpose. Here, the transregulator rtTA mediates expression of a gene of interest after addition of the small molecule effector doxycycline....

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Detalles Bibliográficos
Autores principales: Schmidt, Sebastian, Berens, Christian, Klotzsche, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014509/
https://www.ncbi.nlm.nih.gov/pubmed/24810590
http://dx.doi.org/10.1371/journal.pone.0096546