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PEG-Protein Interaction Induced Contraction of NalD Chains

In a recent attempt to crystallize a regulator of MexAB-OprM multi-drug efflux systems in Pseudomonas aeruginosa (NalD), we found that adding polyethylene glycol (PEG3350, Mw = 3,350 g/mol) into the protein solution increases the speed of NalD migration in gel electrophoresis, signaling a smaller hy...

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Detalles Bibliográficos
Autores principales: Yu, Jiyan, Chen, Weizhong, Wu, Chi, Chen, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014539/
https://www.ncbi.nlm.nih.gov/pubmed/24810951
http://dx.doi.org/10.1371/journal.pone.0096616