A Genome Wide Association Study of Plasmodium falciparum Susceptibility to 22 Antimalarial Drugs in Kenya

BACKGROUND: Drug resistance remains a chief concern for malaria control. In order to determine the genetic markers of drug resistant parasites, we tested the genome-wide associations (GWA) of sequence-based genotypes from 35 Kenyan P. falciparum parasites with the activities of 22 antimalarial drugs...

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Detalles Bibliográficos
Autores principales: Wendler, Jason P., Okombo, John, Amato, Roberto, Miotto, Olivo, Kiara, Steven M., Mwai, Leah, Pole, Lewa, O'Brien, John, Manske, Magnus, Alcock, Dan, Drury, Eleanor, Sanders, Mandy, Oyola, Samuel O., Malangone, Cinzia, Jyothi, Dushyanth, Miles, Alistair, Rockett, Kirk A., MacInnis, Bronwyn L., Marsh, Kevin, Bejon, Philip, Nzila, Alexis, Kwiatkowski, Dominic P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014544/
https://www.ncbi.nlm.nih.gov/pubmed/24809681
http://dx.doi.org/10.1371/journal.pone.0096486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014544/
https://www.ncbi.nlm.nih.gov/pubmed/24809681
http://dx.doi.org/10.1371/journal.pone.0096486

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