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Inter-Species Cross-Seeding: Stability and Assembly of Rat - Human Amylin Aggregates
Diseases such as type 2 diabetes, Alzheimer’s and Parkinson’s share as common feature the accumulation of mis-folded disease-specific protein aggregates into fibrillar structures, or plaques. These fibrils may either be toxic by themselves, or act as reservoirs for smaller cytotoxic oligomers. This...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014569/ https://www.ncbi.nlm.nih.gov/pubmed/24810618 http://dx.doi.org/10.1371/journal.pone.0097051 |