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Directed Evolution of Improved Zinc Finger Methyltransferases
The ability to target DNA methylation toward a single, user-designated CpG site in vivo may have wide applicability for basic biological and biomedical research. A tool for targeting methylation toward single sites could be used to study the effects of individual methylation events on transcription,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014571/ https://www.ncbi.nlm.nih.gov/pubmed/24810747 http://dx.doi.org/10.1371/journal.pone.0096931 |