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Inhibition of Tumor Vasculogenic Mimicry and Prolongation of Host Survival in Highly Aggressive Gallbladder Cancers by Norcantharidin via Blocking the Ephrin Type a Receptor 2/Focal Adhesion Kinase/Paxillin Signaling Pathway

Vasculogenic mimicry (VM) is a newly-defined tumor microcirculation pattern in highly aggressive malignant tumors. We recently reported tumor growth and VM formation of gallbladder cancers through the contribution of the ephrin type a receptor 2 (EphA2)/focal adhesion kinase (FAK)/Paxillin signaling...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Sun, Wei, Zhang, Wen-Zhong, Ge, Chun-Yan, Zhang, Jing-Tao, Liu, Zhong-Yan, Fan, Yue-Zu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014585/
https://www.ncbi.nlm.nih.gov/pubmed/24811250
http://dx.doi.org/10.1371/journal.pone.0096982