Suppression of Akt-mTOR Pathway-A Novel Component of Oncogene Induced DNA Damage Response Barrier in Breast Tumorigenesis

DNA damage has been thought to be directly associated with the neoplastic progression by enabling mutations in tumor suppressor genes and activating/and amplifying oncogenes ultimately resulting in genomic instability. DNA damage causes activation of the DNA damage response (DDR) that is an importan...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Anjana, Rosen, Daniel, Liu, Mei, Liu, Yan, Hao, Qiang, Ganesan, Nivetha, Etzel, Carol J., Gullett, Ashley, Albarracin, Constance T., Bedrosian, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014598/
https://www.ncbi.nlm.nih.gov/pubmed/24811059
http://dx.doi.org/10.1371/journal.pone.0097076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014598/
https://www.ncbi.nlm.nih.gov/pubmed/24811059
http://dx.doi.org/10.1371/journal.pone.0097076

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