“Specificity Determinants” Improve Therapeutic Indices of Two Antimicrobial Peptides Piscidin 1 and Dermaseptin S4 against the Gram-negative Pathogens Acinetobacter baumannii and Pseudomonas aeruginosa

A new class of antimicrobial agents with lower rates of resistance and different targets is urgently needed because of the rapidly increasing resistance to classical antibiotics. Amphipathic cationic α-helical antimicrobial peptides (AMPs) represent such a class of compounds. In our previous studies...

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Detalles Bibliográficos
Autores principales: Jiang, Ziqing, Vasil, Adriana I., Vasil, Michael L., Hodges, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014698/
https://www.ncbi.nlm.nih.gov/pubmed/24670666
http://dx.doi.org/10.3390/ph7040366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014698/
https://www.ncbi.nlm.nih.gov/pubmed/24670666
http://dx.doi.org/10.3390/ph7040366

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