The Carboxy Terminal Region of the Human Cytomegalovirus Immediate Early 1 (IE1) Protein Disrupts Type II Inteferon Signaling

Interferons (IFNs) activate the first lines of defense against viruses, and promote innate and adaptive immune responses to viruses. We report that the immediate early 1 (IE1) protein of human cytomegalovirus (HCMV) disrupts signaling by IFNγ. The carboxyl-terminal region of IE1 is required for this...

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Detalles Bibliográficos
Autores principales: Raghavan, Bindu, Cook, Charles H., Trgovcich, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014707/
https://www.ncbi.nlm.nih.gov/pubmed/24699362
http://dx.doi.org/10.3390/v6041502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014707/
https://www.ncbi.nlm.nih.gov/pubmed/24699362
http://dx.doi.org/10.3390/v6041502

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