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Extracellular Hb Enhances Cardiac Toxicity in Endotoxemic Guinea Pigs: Protective Role of Haptoglobin

Endotoxemia plays a major causative role in the myocardial injury and dysfunction associated with sepsis. Extracellular hemoglobin (Hb) has been shown to enhance the pathophysiology of endotoxemia. In the present study, we examined the myocardial pathophysiology in guinea pigs infused with lipopolys...

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Detalles Bibliográficos
Autores principales: Baek, Jin Hyen, Zhang, Xiaoyuan, Williams, Matthew C., Schaer, Dominik J., Buehler, Paul W., D’Agnillo, Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014731/
https://www.ncbi.nlm.nih.gov/pubmed/24691127
http://dx.doi.org/10.3390/toxins6041244