Recombinant Expression and Functional Characterization of Martentoxin: A Selective Inhibitor for BK Channel (α + β4)

Martentoxin (MarTX), a 37-residue peptide purified from the venom of East-Asian scorpion (Buthus martensi Karsch), was capable of blocking large-conductance Ca(2+)-activated K(+) (BK) channels. Here, we report an effective expression and purification approach for this toxin. The cDNA encoding marten...

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Detalles Bibliográficos
Autores principales: Tao, Jie, Zhou, Zhi Lei, Wu, Bin, Shi, Jian, Chen, Xiao Ming, Ji, Yong Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014743/
https://www.ncbi.nlm.nih.gov/pubmed/24759175
http://dx.doi.org/10.3390/toxins6041419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014743/
https://www.ncbi.nlm.nih.gov/pubmed/24759175
http://dx.doi.org/10.3390/toxins6041419

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