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Recombinant Expression and Functional Characterization of Martentoxin: A Selective Inhibitor for BK Channel (α + β4)
Martentoxin (MarTX), a 37-residue peptide purified from the venom of East-Asian scorpion (Buthus martensi Karsch), was capable of blocking large-conductance Ca(2+)-activated K(+) (BK) channels. Here, we report an effective expression and purification approach for this toxin. The cDNA encoding marten...
Autores principales: | Tao, Jie, Zhou, Zhi Lei, Wu, Bin, Shi, Jian, Chen, Xiao Ming, Ji, Yong Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014743/ https://www.ncbi.nlm.nih.gov/pubmed/24759175 http://dx.doi.org/10.3390/toxins6041419 |
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