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Physiologically Based Pharmacokinetic (PBPK) Modeling of Interstrain Variability in Trichloroethylene Metabolism in the Mouse

Background: Quantitative estimation of toxicokinetic variability in the human population is a persistent challenge in risk assessment of environmental chemicals. Traditionally, interindividual differences in the population are accounted for by default assumptions or, in rare cases, are based on huma...

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Detalles Bibliográficos
Autores principales:	Chiu, Weihsueh A., Campbell, Jerry L., Clewell, Harvey J., Zhou, Yi-Hui, Wright, Fred A., Guyton, Kathryn Z., Rusyn, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	NLM-Export 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014769/ https://www.ncbi.nlm.nih.gov/pubmed/24518055 http://dx.doi.org/10.1289/ehp.1307623

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