Effect of long‐term treatment with a small‐molecule glucokinase activator on glucose metabolism, lipid profiles and hepatic function

We investigated the long‐term effect of a glucokinase (GK) activator (GKA) on the changes in hepatic gene expression, glucose metabolism, lipid profiles and hepatic function in wild‐type mice and the haploinsufficiency of β‐cell‐specific GK mice on a high‐fat (HF) diet. Twenty weeks of GKA treatment...

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Detalles Bibliográficos
Autores principales: Nakamura, Akinobu, Shimazaki, Hiroko, Ohyama, Sumika, Eiki, Junichi, Terauchi, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014967/
https://www.ncbi.nlm.nih.gov/pubmed/24843498
http://dx.doi.org/10.1111/j.2040-1124.2011.00104.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014967/
https://www.ncbi.nlm.nih.gov/pubmed/24843498
http://dx.doi.org/10.1111/j.2040-1124.2011.00104.x

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