Coupling of Two Non-processive Myosin 5c Dimers Enables Processive Stepping along Actin Filaments

Myosin 5c (Myo5c) is a low duty ratio, non-processive motor unable to move continuously along actin filaments though it is believed to participate in secretory vesicle trafficking in vertebrate cells. Here, we measured the ATPase kinetics of Myo5c dimers and tested the possibility that the coupling...

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Detalles Bibliográficos
Autores principales: Gunther, Laura K., Furuta, Ken'ya, Bao, Jianjun, Urbanowski, Monica K., Kojima, Hiroaki, White, Howard D., Sakamoto, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014986/
https://www.ncbi.nlm.nih.gov/pubmed/24809456
http://dx.doi.org/10.1038/srep04907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014986/
https://www.ncbi.nlm.nih.gov/pubmed/24809456
http://dx.doi.org/10.1038/srep04907

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