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Compact representation of k-mer de Bruijn graphs for genome read assembly

BACKGROUND: Processing of reads from high throughput sequencing is often done in terms of edges in the de Bruijn graph representing all k-mers from the reads. The memory requirements for storing all k-mers in a lookup table can be demanding, even after removal of read errors, but can be alleviated b...

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Detalles Bibliográficos
Autor principal: Rødland, Einar Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015147/
https://www.ncbi.nlm.nih.gov/pubmed/24152242
http://dx.doi.org/10.1186/1471-2105-14-313