Stress induced telomere shortening: longer life with less mutations?

BACKGROUND: Mutations accumulate as a result of DNA damage and imperfect DNA repair machinery. In higher eukaryotes the accumulation and spread of mutations is limited in two primary ways: through p53-mediated programmed cell death and cellular senescence mediated by telomeres. Telomeres shorten at...

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Detalles Bibliográficos
Autor principal: Trusina, Ala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015310/
https://www.ncbi.nlm.nih.gov/pubmed/24580844
http://dx.doi.org/10.1186/1752-0509-8-27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015310/
https://www.ncbi.nlm.nih.gov/pubmed/24580844
http://dx.doi.org/10.1186/1752-0509-8-27

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