Intracisternal delivery of AAV9 results in oligodendrocyte and motor neuron transduction in the whole central nervous system of cats

Systemic and intracerebrospinal fluid delivery of adeno-associated virus serotype 9 (AAV9) has been shown to achieve widespread gene delivery to the central nervous system (CNS). However, after systemic injection, the neurotropism of the vector has been reported to vary according to age at injection...

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Detalles Bibliográficos
Autores principales: Bucher, T, Dubreil, L, Colle, M-A, Maquigneau, M, Deniaud, J, Ledevin, M, Moullier, P, Joussemet, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015314/
https://www.ncbi.nlm.nih.gov/pubmed/24572783
http://dx.doi.org/10.1038/gt.2014.16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015314/
https://www.ncbi.nlm.nih.gov/pubmed/24572783
http://dx.doi.org/10.1038/gt.2014.16

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