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Maternal nutrition at conception modulates DNA methylation of human metastable epialleles

In experimental animals, maternal diet during the periconceptional period influences the establishment of DNA methylation at metastable epialleles in the offspring, with permanent phenotypic consequences. Pronounced naturally occurring seasonal differences in the diet of rural Gambian women allowed...

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Detalles Bibliográficos
Autores principales: Dominguez-Salas, Paula, Moore, Sophie E., Baker, Maria S., Bergen, Andrew W., Cox, Sharon E., Dyer, Roger A., Fulford, Anthony J., Guan, Yongtao, Laritsky, Eleonora, Silver, Matt J., Swan, Gary E., Zeisel, Steven H., Innis, Sheila M., Waterland, Robert A., Prentice, Andrew M., Hennig, Branwen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015319/
https://www.ncbi.nlm.nih.gov/pubmed/24781383
http://dx.doi.org/10.1038/ncomms4746