The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

Increased intake of dietary carbohydrate that is fermented in the colon by the microbiota has been reported to decrease body weight, although the mechanism remains unclear. Here we use in vivo(11)C-acetate and PET-CT scanning to show that colonic acetate crosses the blood–brain barrier and is taken...

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Detalles Bibliográficos
Autores principales: Frost, Gary, Sleeth, Michelle L., Sahuri-Arisoylu, Meliz, Lizarbe, Blanca, Cerdan, Sebastian, Brody, Leigh, Anastasovska, Jelena, Ghourab, Samar, Hankir, Mohammed, Zhang, Shuai, Carling, David, Swann, Jonathan R., Gibson, Glenn, Viardot, Alexander, Morrison, Douglas, Louise Thomas, E, Bell, Jimmy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015327/
https://www.ncbi.nlm.nih.gov/pubmed/24781306
http://dx.doi.org/10.1038/ncomms4611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015327/
https://www.ncbi.nlm.nih.gov/pubmed/24781306
http://dx.doi.org/10.1038/ncomms4611

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