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GATA-dependent regulatory switches establish atrioventricular canal specificity during heart development

The embryonic vertebrate heart tube develops an atrioventricular canal that divides the atrial and ventricular chambers, forms atrioventricular conduction tissue and organizes valve development. Here we assess the transcriptional mechanism underlying this localized differentiation process. We show t...

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Detalles Bibliográficos
Autores principales: Stefanovic, Sonia, Barnett, Phil, van Duijvenboden, Karel, Weber, David, Gessler, Manfred, Christoffels, Vincent M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015328/
https://www.ncbi.nlm.nih.gov/pubmed/24770533
http://dx.doi.org/10.1038/ncomms4680