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GATA-dependent regulatory switches establish atrioventricular canal specificity during heart development
The embryonic vertebrate heart tube develops an atrioventricular canal that divides the atrial and ventricular chambers, forms atrioventricular conduction tissue and organizes valve development. Here we assess the transcriptional mechanism underlying this localized differentiation process. We show t...
Autores principales: | Stefanovic, Sonia, Barnett, Phil, van Duijvenboden, Karel, Weber, David, Gessler, Manfred, Christoffels, Vincent M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015328/ https://www.ncbi.nlm.nih.gov/pubmed/24770533 http://dx.doi.org/10.1038/ncomms4680 |
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