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Synthetic Studies Towards the Core Structure of Nakadomarin A by a Thioamide-Based Strategy

The tricyclic BCD substructure of the marine natural product nakadomarin A has been synthesised. The strategy utilised a key carbon–carbon bond-forming reaction between a furan and an N-acyliminium ion derived from a secondary thiolactam. In addition, a novel three-component coupling reaction betwee...

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Detalles Bibliográficos
Autores principales: Chavda, Jai K, Procopiou, Panayiotis A, Horton, Peter N, Coles, Simon J, Porter, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015372/
https://www.ncbi.nlm.nih.gov/pubmed/24829538
http://dx.doi.org/10.1002/ejoc.201301063