Cargando…

Synthetic Studies Towards the Core Structure of Nakadomarin A by a Thioamide-Based Strategy

The tricyclic BCD substructure of the marine natural product nakadomarin A has been synthesised. The strategy utilised a key carbon–carbon bond-forming reaction between a furan and an N-acyliminium ion derived from a secondary thiolactam. In addition, a novel three-component coupling reaction betwee...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chavda, Jai K, Procopiou, Panayiotis A, Horton, Peter N, Coles, Simon J, Porter, Michael J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2014
Materias:	Full Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015372/ https://www.ncbi.nlm.nih.gov/pubmed/24829538 http://dx.doi.org/10.1002/ejoc.201301063

Ejemplares similares

A novel method for heterocyclic amide–thioamide transformations
por: Fathalla, Walid, et al.
Publicado: (2017)

Partial thioamide scan on the lipopeptaibiotic trichogin GA IV. Effects on folding and bioactivity
por: De Zotti, Marta, et al.
Publicado: (2012)

Dimethylamine as the key intermediate generated in situ from dimethylformamide (DMF) for the synthesis of thioamides
por: Liu, Weibing, et al.
Publicado: (2015)

An efficient metal-free and catalyst-free C–S/C–O bond-formation strategy: synthesis of pyrazole-conjugated thioamides and amides
por: Sharma, Shubham, et al.
Publicado: (2023)

Regioselective synthesis of heterocyclic N-sulfonyl amidines from heteroaromatic thioamides and sulfonyl azides
por: Ilkin, Vladimir, et al.
Publicado: (2020)

A chromatography-free and aqueous waste-free process for thioamide preparation with Lawesson’s reagent
por: Wu, Ke, et al.
Publicado: (2021)

Eschenmoser coupling reactions starting from primary thioamides. When do they work and when not?
por: Marek, Lukáš, et al.
Publicado: (2023)

Structural impact of thioamide incorporation into a β-hairpin
por: Fiore, Kristen E., et al.
Publicado: (2022)

Adamantane-1-thioamide
por: Zahid, Maryam, et al.
Publicado: (2009)

Transmembrane anion transport promoted by thioamides
por: Pomorski, Robert, et al.
Publicado: (2021)

Towards Symmetric Thioamides: Microwave-Aided Synthesis of Terephthalic Acid Derivatives
por: Bak, Andrzej, et al.
Publicado: (2023)

Interaction of Thioamides, Selenoamides, and Amides With Diiodine
por: Hadjikakou, Sotiris K., et al.
Publicado: (2006)

Thioamide-Based Fluorescent Protease Sensors
por: Goldberg, Jacob M., et al.
Publicado: (2014)

Catalytic Hydrogenation of Thioesters, Thiocarbamates, and Thioamides
por: Luo, Jie, et al.
Publicado: (2020)

Nitroalkanes as thioacyl equivalents to access thioamides and thiopeptides
por: Wang, Xiaonan, et al.
Publicado: (2023)

Practical synthetic strategies towards lipophilic 6-iodotetrahydroquinolines and -dihydroquinolines
por: Chisholm, David R, et al.
Publicado: (2016)

One-pot synthesis of 2-arylated and 2-alkylated benzoxazoles and benzimidazoles based on triphenylbismuth dichloride-promoted desulfurization of thioamides
por: Koyanagi, Arisu, et al.
Publicado: (2022)

Reconstitution of Iterative Thioamidation in Closthioamide Biosynthesis Reveals Tailoring Strategy for Nonribosomal Peptide Backbones
por: Dunbar, Kyle L., et al.
Publicado: (2019)

Mechanism of thioamide drug action against tuberculosis and leprosy
por: Wang, Feng, et al.
Publicado: (2007)

Thioamide substitution to probe the hydroxyproline recognition of VHL ligands
por: Soares, Pedro, et al.
Publicado: (2018)

Increasing the bioactive space of peptide macrocycles by thioamide substitution
por: Verma, Hitesh, et al.
Publicado: (2018)

Palladium-catalyzed Suzuki-Miyaura coupling of thioureas or thioamides
por: Mai, Shaoyu, et al.
Publicado: (2019)

Functional Elucidation of TfuA in Peptide Backbone Thioamidation
por: Liu, Andi, et al.
Publicado: (2021)

Synthetic studies towards bottromycin
por: Ackermann, Stefanie, et al.
Publicado: (2012)

Divergent regioselectivity in photoredox-catalyzed hydrofunctionalization reactions of unsaturated amides and thioamides
por: Morse, Peter D., et al.
Publicado: (2015)

Towards More Practical Methods for the Chemical Synthesis of Thioamides Using Sulfuration Agents: A Decade Update
por: Zhang, Qiang, et al.
Publicado: (2023)

Correction: Masking thiol reactivity with thioamide, thiourea, and thiocarbamate-based MBPs
por: Seo, Hyeonglim, et al.
Publicado: (2023)

Synthetic study toward tridachiapyrone B
por: Cormier, Morgan, et al.
Publicado: (2022)

N-(2,6-Diisopropylphenyl)thioamide
por: Omondi, Bernard, et al.
Publicado: (2012)

n→π* Interactions of Amides and Thioamides: Implications for Protein Stability
por: Newberry, Robert W., et al.
Publicado: (2013)

Thyroidectomy for the treatment of Graves’ thyrotoxicosis in thioamide-induced agranulocytosis and sepsis
por: Knight, Colin L, et al.
Publicado: (2017)

Design, Synthesis, and Biological Evaluations of Novel Azothiazoles Based on Thioamide
por: Sayed, Abdelwahed R., et al.
Publicado: (2022)

Transformation of Amides to Thioamides Using an Efficient and Novel Thiating Reagent
por: Gomaa, Mohamed S., et al.
Publicado: (2022)

An amide to thioamide substitution improves the permeability and bioavailability of macrocyclic peptides
por: Ghosh, Pritha, et al.
Publicado: (2023)

A Synthetic Route Toward Tetrazoles: The Thermolysis of Geminal Diazides
por: Holzschneider, Kristina, et al.
Publicado: (2019)

The Thioamides Methimazole and Thiourea Inhibit Growth of M. avium Subspecies paratuberculosis in Culture
por: Greenstein, Robert J., et al.
Publicado: (2010)

Trypanocidal Activity of Thioamide-Substituted Imidazoquinolinone: Electrochemical Properties and Biological Effects
por: Frank, Fernanda M., et al.
Publicado: (2013)

Managing the retro-pathway in direct catalytic asymmetric aldol reactions of thioamides
por: Bao, Youmei, et al.
Publicado: (2015)

Visible-light-promoted and chlorophyll-catalyzed aerobic desulfurization of thioamides to amides
por: Yang, Zihui, et al.
Publicado: (2022)

Short and Efficient Syntheses of Protoberberine Alkaloids using Palladium-Catalyzed Enolate Arylation**
por: Gatland, Alice E, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_foavisted7oc3lemkrotuka8if