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Selective apoptosis induction in MCF-7 cell line by truncated minimal functional region of Apoptin

BACKGROUND: Chicken Anemia Virus (CAV) VP3 protein (also known as Apoptin), a basic and proline-rich protein has a unique capability in inducing apoptosis in cancer cells but not in normal cells. Five truncated Apoptin proteins were analyzed to determine their selective ability to migrate into the n...

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Detalles Bibliográficos
Autores principales: Shen Ni, Lim, Allaudin, Zeenathul Nazariah bt, Mohd Lila, Mohd Azmi b, Othman, Abas Mazni b, Othman, Fauziah bt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015422/
https://www.ncbi.nlm.nih.gov/pubmed/24144306
http://dx.doi.org/10.1186/1471-2407-13-488