The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation

The Drosophila protein brain tumor (Brat) forms a complex with Pumilio (Pum) and Nanos (Nos) to repress hunchback (hb) mRNA translation at the posterior pole during early embryonic development. It is currently thought that complex formation is initiated by Pum, which directly binds the hb mRNA and s...

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Detalles Bibliográficos
Autores principales: Loedige, Inga, Stotz, Mathias, Qamar, Saadia, Kramer, Katharina, Hennig, Janosch, Schubert, Thomas, Löffler, Patrick, Längst, Gernot, Merkl, Rainer, Urlaub, Henning, Meister, Gunter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015489/
https://www.ncbi.nlm.nih.gov/pubmed/24696456
http://dx.doi.org/10.1101/gad.236513.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015489/
https://www.ncbi.nlm.nih.gov/pubmed/24696456
http://dx.doi.org/10.1101/gad.236513.113

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