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PRDE-1 is a nuclear factor essential for the biogenesis of Ruby motif-dependent piRNAs in C. elegans

Piwi-interacting RNAs (piRNA) are small regulatory RNAs with essential roles in maintaining genome integrity in animals and protists. Most Caenorhabditis elegans piRNAs are transcribed from two genomic clusters that likely contain thousands of individual transcription units; however, their biogenesi...

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Detalles Bibliográficos
Autores principales: Weick, Eva-Maria, Sarkies, Peter, Silva, Nicola, Chen, Ron A., Moss, Sylviane M.M., Cording, Amy C., Ahringer, Julie, Martinez-Perez, Enrique, Miska, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015492/
https://www.ncbi.nlm.nih.gov/pubmed/24696457
http://dx.doi.org/10.1101/gad.238105.114