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PID-1 is a novel factor that operates during 21U-RNA biogenesis in Caenorhabditis elegans

The Piwi–piRNA pathway represents a small RNA-based mechanism responsible for the recognition and silencing of invading DNA. Biogenesis of piRNAs (21U-RNAs) is poorly understood. In Caenorhabditis elegans, the piRNA-binding Argonaute protein PRG-1 is the only known player acting downstream from prec...

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Detalles Bibliográficos
Autores principales: de Albuquerque, Bruno F.M., Luteijn, Maartje J., Cordeiro Rodrigues, Ricardo J., van Bergeijk, Petra, Waaijers, Selma, Kaaij, Lucas J.T., Klein, Holger, Boxem, Mike, Ketting, René F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015495/
https://www.ncbi.nlm.nih.gov/pubmed/24696453
http://dx.doi.org/10.1101/gad.238220.114