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PID-1 is a novel factor that operates during 21U-RNA biogenesis in Caenorhabditis elegans
The Piwi–piRNA pathway represents a small RNA-based mechanism responsible for the recognition and silencing of invading DNA. Biogenesis of piRNAs (21U-RNAs) is poorly understood. In Caenorhabditis elegans, the piRNA-binding Argonaute protein PRG-1 is the only known player acting downstream from prec...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015495/ https://www.ncbi.nlm.nih.gov/pubmed/24696453 http://dx.doi.org/10.1101/gad.238220.114 |