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Polyol pathway and diabetic nephropathy revisited: Early tubular cell changes and glomerulopathy in diabetic mice overexpressing human aldose reductase

Aims/Introduction:  The polyol pathway has long been involved in the pathogenesis of diabetic nephropathy. It remains still unclear, however, how the polyol pathway is implicated in this process. We explored the effects of the enhanced polyol pathway on renocortical tubular cells and glomeruli in ex...

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Detalles Bibliográficos
Autores principales: Hashimoto, Yasuhiro, Yamagishi, Shin‐Ichiro, Mizukami, Hiroki, Yabe‐Nishimura, Chihiro, Lim, Sun Woo, Kwon, H Moo, Yagihashi, Soroku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015536/
https://www.ncbi.nlm.nih.gov/pubmed/24843470
http://dx.doi.org/10.1111/j.2040-1124.2010.00071.x