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Exploring evolution of brain genes involved in microcephaly through phylogeny and synteny analysis

BACKGROUND: Human brain development is a complicated process. When normal growth and development of brain or central nervous system is impaired, it leads to neurodevelopemental disorders (NDDs). Autosomal Recessive Primary Microcephaly (MCPH) is one of those, for which seven loci (MCPH1-MCPH7) with...

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Detalles Bibliográficos
Autores principales: Rauf, Sobiah, Mir, Asif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015606/
https://www.ncbi.nlm.nih.gov/pubmed/24148351
http://dx.doi.org/10.1186/1742-4682-10-61