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Dph7 Catalyzes a Previously Unknown Demethylation Step in Diphthamide Biosynthesis
[Image: see text] Present on archaeal and eukaryotic translation elongation factor 2, diphthamide represents one of the most intriguing post-translational modifications on proteins. The biosynthesis of diphthamide was proposed to occur in three steps requiring seven proteins, Dph1–7, in eukaryotes....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015618/ https://www.ncbi.nlm.nih.gov/pubmed/24739148 http://dx.doi.org/10.1021/ja5009272 |